Drug Synergism

由 JP Griffin 著作 · 被引用 1 次 — In pharmacological terms it has a precise meaning, which is distinct from interaction between two or more active substances where the interaction may be on the ...

由 RJ Tallarida 著作 · 2001 · 被引用 928 次 — Abstract. Two drugs that produce overtly similar effects will sometimes produce exaggerated or diminished effects when used concurrently. A quantitative ...

Clinically, drug synergism can be expected when drugs that act by different mechanisms of action are mixed together. Various drug combinations (e.g., NSAIDs and ...

The synergistic effect of drugs is when two or more drugs are combined, their overall effect is greater than the sum of their individual effects. In most cases, ...

由 RJ Tallarida 著作 · 2011 · 被引用 411 次 — A synergistic interaction allows the use of lower doses of the combination constituents, a situation that may reduce adverse reactions. Drug combinations are ...

Drug synergism can be expected when drugs that act by different mechanisms of action are mixed together. Various drug combinations (e.g., nonsteroidal anti- ...

An interaction between two or more drugs that causes the total effect of the drugs to be greater than the sum of the individual effects of each drug.

Synergism: when the combine effect of two drugs is greater than the sum of their effects when given separately. Potentiation: when one drug does not elicit a ...